About Methadone

‘Methadone’ is used in the maintenance and to treat opioid use disorder, and it includes counselling and other behavioural therapies to provide an individual with a whole-person approach. This medicine belongs to a class of drugs known as Opiates, which is a narcotic analgesic.

It is a long-acting full-opioid agonist and is classified as a Schedule II controlled medicine that is used for people with a confirmed diagnosis of Opioid Use Disorder (OUD). This medication is approved by U.S. Food And Drug Administration (FDA) to treat OUD as well as be beneficial in pain management.

Methadone works by changing the way how the brain and nerves respond to pain. It helps to lessen the pain symptoms of opiate withdrawals. It blocks the euphoric effects of opiate drugs such as opioids, morphine, and codeine, as well as semi-synthetic drugs such as Hydrocodone and oxycodone.

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Why Methadone Is Used

Methadone is used to treat heroin dependence. This medication is used daily to treat the symptoms of heroin withdrawal and to reduce the cravings for taking heroin every day. Methadone has been used for decades to help people who are addicted to opioid drugs, heroin, and narcotic medicines.

Methadone maintenance treatment helps to treat and reduce your illicit drug use. It is a powerful drug used for pain relief and in the effective treatment of drug addiction. 

The active ingredients of Methadone remain in the body for a longer time even after the effects of This medication wear off. If you use any other medication during that time, a serious drug interaction can happen that can cause certain side effects.

This medication should be used under the supervision of a doctor or practitioner when used in opioid use disorder (OUD). Apart from tablets, Methadone is also available in liquid solutions that are directly injected into the body of the patients via injection.

When this medication is used in the treatment of narcotic addiction, Methadone helps to treat and suppress withdrawal symptoms for up to 24 – 36 hours.

How To Take The Doses

The dose of this medication may vary from person to person based on how much dependency and addiction they have on any opioid or narcotic medicines. Your doctor will prescribe your doses according to your response to the medicine.

Any dose of this medication should not be used by a person who is not used to or addicted to any opioid medicines, as it can lead to serious health problems. It is not recommended that this medication be used without a doctor’s prescription.

For Adults With Opioid Use Disorder –

• For adults the initial dose should be 20 – 30 mg tablets to be taken once a day. Your doctor may later adjust your dose according to the response of the medicine. The dose should not exceed more than 40 mg in a day.

For Children With Opioid UseDisorder –

• Children should not use this medication without a doctor’s proper consultation.

Do not increase the dose of this medication unless your doctor tells you to do so. Excessive use of this medication can cause certain severe withdrawal symptoms of this medication. Stick to your prescription, and keep these medications out of reach of children.

Side Effects

If you experience any of the side effects given below while using Methadone, then take immediate medical attention or consult a doctor to treat them effectively before the symptoms get worse and cause any serious health problems.

Some Common Side Effects Of Methadone Include –

• Nausea
• Vomiting 
• Restlessness
• Lightheadedness
• Slow breathing 
• Heavy sweating 
• Constipation 
• Sexual problems

Serious Side Effects Of Methadone Include –

• Skin rashes 
• Itching
• Hives
• Chest pain
• Slow or shallow breathing
• Swelling of face, lips, tongue or throat
• Pounding heart rate
• Hallucination, and 
• Confusion

Excessive use or overdose of this medication can slow or stop your breathing, and when it is left untreated, it can cause seizures.

Methadone can be safely used during pregnancy and breastfeeding as it does not cause any side effects or harm to the baby’s health.

Pregnant women who overdose on Methadone and experience withdrawal symptoms of this medication are at a higher risk of miscarriage and premature birth of the baby because of Uterus contraction caused by withdrawal symptoms. However, during this treatment, parental care should be included to prevent complications during pregnancy and childbirth.

What To Avoid

To prevent any side effects, interactions, and withdrawal symptoms of this medication, consult a doctor and ask about the potential risks of misuse, abuse, and addiction before using this medication.

• Avoid overdosing on Methane, as it can be life-threatening and can slow or stop your breathing till death.
• Do not use any opioid or non-opioid medicines while using this medication or even after the effects of Methadone have worn off to prevent any serious drug interaction.
• Talk to your doctor if you are habitual to alcohol or any other substance, and avoid using them to prevent any withdrawal symptoms.
• Avoid doing any activity that requires your full focus and attention, such as driving, to prevent any accident.
• To prevent constipation, eat dietary fibre, drink enough water, and make sure you are hydrated.

Conclusion

To treat opioid use disorder, this medication should be taken on a doctor’s prescription for safe and effective use and to treat any opioid use disorder or to overcome the addiction to heroin. It is also extensively used in the treatment of pain management and maintenance of (OUD).

If you have any opioid use disorder, then taking these medications with a doctor’s prescription will prove to be beneficial to your health and to overcome opioid dependency. Overdose of this medication in any way can cause serious health problems and, in rare cases, may lead to death.

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