About Hydromorphone

‘Hydromorphone’ is sold under the brand Dilaudid, among others, and it belongs to a class of medicines called opioids, which includes morphine. It is a strong opioid-based pain medicine that can only be prescribed by your doctor and is recommended to be used only for the short-term treatment of pain.

It is a potent opioid medication that is used for moderate to severe acute and acute chronic pain in patients. It is not the same as morphine, but it is much more powerful than that, so be cautious and remember not to confuse the two.

It has a rapid onset of action that makes it more effective in relieving and managing pain. This medication works directly on the opioid receptors in the central nervous system by interrupting the way nerves signal the pain between the brain and the body.

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Why Hydromorphone Is Used

It is utilized to effectively manage and treat moderate to severe acute and acute chronic pain when all other opioid and non-opioid medicines fail to work, are ineffective, and require opioid analgesics to relieve the pain effectively.

Using any other opioid medication while using this medication can cause serious health problems, which may cause serious drug interaction, which can prove to be fatal to one’s health.

Tell your doctor if you are dealing with kidney or liver problems or if you have multiple health conditions before using this medication. Otherwise, it can severely affect and damage your liver.

These medications come in two forms: immediate-release and extended-release tablets. Immediate-release tablets start working immediately provide instant relief from pain and are indicated to be used for short-term treatment of pain. Whereas extended-release tablets take time to work and provide relief over time.

Using Opioids, including hydromorphone, with other CNS depressants, such as (benzodiazepine and barbiturates) can lead to severe respiratory depression and CNS (central nervous system) disorder.

How To Take The Doses

This medication is recommended to be used for short-term treatment of pain, and that too on a doctor’s prescription to avoid and prevent any side effects and adverse effects of this medication.

The dose of this medication may differ from person to person depending on an individual’s age, sex, health conditions, and the strength of the medicines they use. 

For Moderate To Severe Pain –

• The dose of the immediate-release tablet is 2 – 4 mg to be taken every 4 to 6 hours in a day. Your doctor may increase or decrease your doses according to their response to the pain.  
• The usual dose of oral liquid solution is 2.5 – 10 ml to be taken every 2 – 3 hours in a day.

For Chronic Severe Pain –

• Opioid-tolerant patients only recommended to use 8 – 64 mg of extended-release tablets per day. The initial recommended dose for oral liquid solution is 2.5 – 10 mg to be taken every 2 – 3 hours.

Side Effects

Take immediate medical help, if you experience any of the signs or symptoms of side effects to treat it effectively before it can get worse, and become a serious health problem.

Excess use of this medication without a doctor’s prescription can cause various health problems, and it can severely affect the liver, resulting in liver damage.

Some Common Side Effects Of Hydromorphone Include –

• Dizziness
• Drowsiness
• Lightheadedness
• Nausea
• Vomiting
• Dry mouth
• Sweating
• Euphoria
• Constipation 
• Headaches
• Fatigue

Some Serious Side Effects Of Hydromorphone Include –

• Heart problem 
• Vision changes
• Stomach problem
• Extreme drowsiness
• Mood or behavioral changes
• Nervous system and muscle problems 
• Change in blood pressure
• Adrenal insufficiency
• Androgen insufficiency
• Trouble breathing and shortness of breath

Allergic Reactions Of Hydromorphone Include –

• Skin rashes
• Itching
• Hives
• Swelling

The risks of side effects are higher –

• If you are using Hydromorphone for the first time
• If the dose of Hydromorphone increases
• If you are suffering from a liver disease
• If you are 65 years old or older than that
• If you are suffering from multiple health conditions

What To Avoid

Before using this medication, ask your doctor about the side effects and potential health problems that it can cause when misused by a person without a doctor’s prescription.

• Avoid using hydromorphone and alcohol together, as it can considerably increase the risk of respiratory depression.
• Do not use this medication if you have kidney or liver problems, as it has the potential to affect and damage your liver severely.
• Avoid using this medication if you have an allergic reaction to Hydromorphone or any of the opioid medications.
• Pregnant women and breastfeeding mothers should not use this medication without a doctor’s prescription.
• Eat dietary fibers, drink enough water, and consume liquid-based food to prevent constipation.

Conclusion 

Hydromorphone is mainly used to relieve pain and alleviate discomfort and is indicated to be used for a short-term period. These medications give a higher risk of abuse, misuse, and addiction, and using them for a longer period can develop dependency and lead to addiction.

Suddenly, stopping the use of this medication after using it for a longer period can cause certain severe withdrawal symptoms that may be life-threatening to your health.

It is advised only to use this medication on a doctor’s prescription when all other opioid and non-opioid medications don’t work or are ineffective on the pain.

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